In addition to the mentioned side effects several others have been reported. In both males and females acne are frequently reported, as well as hypertrophy of sebaceous glands, increased tallow excretion, hair loss, and alopecia. There is some evidence that anabolic steroid abuse may affect the immune system, leading to a decreased effectiveness of the defense system. Steroid use decreases the glucose tolerance, while there is an increase in insulin resistance. These changes mimic Type II diabetes. These changes seem to be reversible after abstention from the drugs.
Given the nature of many of the androgenic and estrogenic side effects from Trenbolone, it is often difficult to minimize the risk of negative effects while still preserving the efficacy of the drug. There are certainly methods that bodybuilders use to minimize the likelihood of harmful reactions, and the most important would be only taking anabolic-androgenic steroids under the supervision of a doctor who is well-versed in steroid use.
I think that if most bodybuilders objectively consider the long-term risks versus the short-term gains, it really won’t seem worth it in the end.
Drug Enforcement Administration. “Human Growth Hormone”; DEA fact sheet; August 2013. <http:///drug_chem_info/>
Dunkin, Mary Anne. “Human Growth Hormone (HGH)”; WebMD; December 30, 2014. <http:///fitness-exercise/human-growth-hormone-hgh>
Fordyce, Tom. “Human Growth Hormone Explained”; BBC Sport; July 27, 2003. <http:///sport2/hi/front_page/>
Jackson, Joe. “Unlock Your Potential: How to Boost Your HGH Levels”; Men’s Fitness; accessed June 5, 2015. <http:///nutrition/supplements/unlock-your-potential-how-to-boost-your-hgh-levels>
Mayo Clinic. “Drugs and Supplements: Growth Hormone (Parenteral Route)”; May Clinic website; last updated April, 2015. <http:///drugs-supplements/growth-hormone-parenteral-route/description/drg-20069416>
Mayo Clinic Staff. “Human Growth Hormone: Does It Slow Aging?”; Mayo Clinic website; February 1, 2014. <http:///healthy-lifestyle/healthy-aging/in-depth/growth-hormone/art-20045735>
Mayo Clinic Staff. “Performance-Enhancing Drugs: Know the Risks”; Mayo Clinic website; December 12, 2012. <http:///healthy-lifestyle/fitness/in-depth/performance-enhancing-drugs/art-20046134>