According to the International Programme on Chemical Safety (IPCS) and United States Food and Drug Administration (USFDA), [note 5] amphetamine is contraindicated in people with a history of drug abuse , [note 6] cardiovascular disease , severe agitation , or severe anxiety.    It is also contraindicated in people currently experiencing advanced arteriosclerosis (hardening of the arteries), glaucoma (increased eye pressure), hyperthyroidism (excessive production of thyroid hormone), or moderate to severe hypertension .    People who have experienced allergic reactions to other stimulants in the past or who are taking monoamine oxidase inhibitors (MAOIs) are advised not to take amphetamine,    although safe concurrent use of amphetamine and monoamine oxidase inhibitors has been documented.   These agencies also state that anyone with anorexia nervosa , bipolar disorder , depression, hypertension, liver or kidney problems, mania , psychosis , Raynaud's phenomenon , seizures , thyroid problems, tics , or Tourette syndrome should monitor their symptoms while taking amphetamine.   Evidence from human studies indicates that therapeutic amphetamine use does not cause developmental abnormalities in the fetus or newborns (., it is not a human teratogen ), but amphetamine abuse does pose risks to the fetus.  Amphetamine has also been shown to pass into breast milk, so the IPCS and USFDA advise mothers to avoid breastfeeding when using it.   Due to the potential for reversible growth impairments, [note 7] the USFDA advises monitoring the height and weight of children and adolescents prescribed an amphetamine pharmaceutical. 
“Depression and anxiety sort of run in my family but I always said I didn't have that affliction. Eventually my grandmother told me she could tell from some of the things I said that I did have some degree of depression. I wasn't convinced. Then I started taking Flavay and Flavay Plus and I felt a new positive psychological outlook. Sometimes I would take 2 capsules of each and sometimes 4 capsules of each since I had read online that some people like taking 4 of each better. When I ran out of Flavay and Flavay Plus I didn't reorder because I was feeling so good.