In 2006, Giannoulis et al. (11) investigated the effects of growth hormone and/or Te in healthy elderly men. This six month double-blind study consisted of men ages 65-80 grouped into 4 areas: 1) Placebo GH and Te, 2) GH and placebo Te, 3) placebo GH and Te, or 4) GH and Te. The results of this study were administration of both GH and Te in older men had more positive effects than the other groups, including increased lean body mass (P = ), muscle size (P = ), and aerobic capacity (P < ). Notably, lean body mass did increase with GH administration only as compared to placebo group.
Common (1% to 10%): Sinusitis, nasopharyngitis, upper respiratory tract infection , bronchitis
Uncommon (% to 1%): Cough, dyspnea, snoring, dysphonia
Rare (less than %): Pulmonary microembolism (POME) (cough, dyspnea, malaise, hyperhidrosis, chest pain, dizziness, paresthesia, or syncope) caused by oily solutions
Frequency not reported: Sleep apnea
Postmarketing reports: Chest pain, asthma , chronic obstructive pulmonary disease , hyperventilation, obstructive airway disorder, pharyngeal edema, pharyngolaryngeal pain, pulmonary embolism , respiratory distress, rhinitis , sleep apnea syndrome [ Ref ]