Women going through hormone changes later in life can be difficult. With multiple hormones taking effect in a woman’s body the effects hormone deficiency can be almost intolerable. With our hormone replacement therapy treatments we help stabilize the levels of hormones in your body to bring you back to a time you can enjoy again. Hormone deficiency affects almost all women. So you are not alone. With our treatment plans, we customize your hormone levels to the levels that you feel the best. Our treatment plans are never one-size-fits-all.
Another question is the possible value of adding chemotherapy to hormone therapy as initial treatment for men with hormone-sensitive metastatic prostate cancer. Currently, chemotherapy is not used in these men until their disease progresses on hormone therapy (., until it becomes hormone resistant). Early results of an NCI-sponsored trial that was conducted by two cancer cooperative groups—the Eastern Cooperative Oncology Group (ECOG) and the American College of Radiology Imaging Network (ACRIN)—suggest that men with hormone-sensitive metastatic prostate cancer who receive the chemotherapy drug docetaxel at the start of standard hormone therapy live longer than men who receive hormone therapy alone. The trial results suggested that men with the most extensive metastatic disease benefit the most from the early addition of docetaxel. A follow-up analysis will be performed to clarify the effect of this treatment on men with less extensive metastatic disease.
There is considerable controversy over the earliest age at which it is clinically, morally, and legally safe to use GnRH analogues, and for how long. The sixth edition of the World Professional Association for Transgender Health 's Standards of Care permit it from Tanner stage 2 but do not allow the addition of hormones until age 16, which could be five or more years later. Sex steroids have important functions in addition to their role in puberty, and some skeletal changes (such as increased height) that may be considered masculine are not hindered by GnRH analogues.