Haldol decanoate spc

The influence of renal impairment on the pharmacokinetics of haloperidol has not been evaluated. About one-third of a haloperidol dose is excreted in urine, mostly as metabolites. Less than 3% of administered haloperidol is eliminated unchanged in the urine. Haloperidol metabolites are not considered to make a significant contribution to its activity, although for the reduced metabolite of haloperidol, back-conversion to haloperidol cannot be fully ruled out. Even though impairment of renal function is not expected to affect haloperidol elimination to a clinically relevant extent, caution is advised in patients with renal impairment, and especially those with severe impairment, due to the long half-life of haloperidol and its reduced metabolite, and the possibility of accumulation (see section ).

Ensure patient is maintained on specific manufacturer's product (MHRA 2013).
No monitoring of drug levels required to optimise or to monitor treatment.
Prescriptions for phenobarbital (phenobarbitone) must comply with the following legal requirements:

  • the prescription must be signed and dated by the prescriber.
  • the handwritten or computer-generated script must state:
    • the name and address of the patient.
    • the form and strength of the preparation.
    • the dose (note “as directed” does not constitute a dose).
    • the total quantity of the preparation in words and figures.
PHENYTOIN

Haldol decanoate spc

haldol decanoate spc

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haldol decanoate spc

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