From all the forms of steroids that are available in the market you will find that there are a large number of steroids that are available in the both oral as well as injectable form. While comparing the oral and injectable form, more stability with some quality gains would be achieved by using injectable form of the steroids. But there are some higher amount of side effects associated with the injectable form. The first thing is that the user must not make any mistake while administrating the injectable form of steroid in the body. There are some anabolic androgenic steroids that are not available in both forms while there are some whose oral form is less effective than the injectable form and vice versa. Some of these steroids are being discussed here.
The primary endpoint is 2 year progression free survival. With 390 patients (248 PFS events) there will be 80% power to detect a 13% difference in 2 year PFS assuming the 2 year PFS in the control arm (TIP) is 30%. There will also be 54% to 71% power to detect a difference of 12% in 3 year overall survival, the most important secondary endpoint of the trial. This value will depend on the 3 year overall survival of TIP-treated patients, which is estimated to be 50% based on the values from the IT94 CDCT arm & the large retrospective observational study [ 5 , 10 ].