Boldenone vs testosterone

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Testosterone can be administered parenterally , but it has more irregular prolonged absorption time and greater activity in muscle in enanthate , undecanoate , or cypionate ester form. These derivatives are hydrolyzed to release free testosterone at the site of injection; absorption rate (and thus injection schedule) varies among different esters, but medical injections are normally done anywhere between semi-weekly to once every 12 weeks. A more frequent schedule may be desirable in order to maintain a more constant level of hormone in the system. [57] Injectable steroids are typically administered into the muscle, not into the vein, to avoid sudden changes in the amount of the drug in the bloodstream. In addition, because estered testosterone is dissolved in oil, intravenous injection has the potential to cause a dangerous embolism (clot) in the bloodstream.

ONC1-0013B inhibits AR activity in vitro. A. ONC1-0013B structure. B. LnCAP cells cultured (10% CSS) for 3 days, then treated with tested compounds in presence of 1nM DHT for 1 day. PSA expression plotted as percentage of vehicle control (DMSO; n=2, mean±SEM). Ki values: ± (ONC1-13B), ± (MDV3100), (ARN-509). Mean±SEM from 5 replicate experiments (except ARN-509). C. LnCAP cells cultured (10% CSS) for 3 days, then treated with tested compounds in presence of 1nM DHT for 5 days. Viable cells plotted as percentage of vehicle control (DMSO; n=2, mean±SEM). IC50 values: 30nM (ONC1-13B), 148nM (MDV3100), 240nM (ARN-509). D. Competitive-binding assay vs AR ligand Fluormone™ (PolarScreen™ Androgen Receptor Competitor Assay). IC50 values: 19nM (DHT), (ONC1-13B), (MDV3100).

[ Editor's Note: Chryste Gaines, MBA, Olympic gold and bronze medal sprinter and former teammate of Marion Jones in the 2000 Sydney Olympic Games, stated the following in a Dec. 22, 2008 email to in response to the IOC ruling:

"We are being unfairly punished. If the drug testing agencies cannot determine if an athlete is taking performance enhancing drugs how are the teammates supposed to know?... It negates all the family functions, church functions, and social events we missed in the name of winning an Olympic medal." ]

Testosterone is significantly correlated with aggression and competitive behaviour and is directly facilitated by the latter. There are two theories on the role of testosterone in aggression and competition. [78] The first one is the challenge hypothesis which states that testosterone would increase during puberty thus facilitating reproductive and competitive behaviour which would include aggression. [78] Thus it is the challenge of competition among males of the species that facilitates aggression and violence. [78] Studies conducted have found direct correlation between testosterone and dominance especially among the most violent criminals in prison who had the highest testosterone levels. [78] The same research also found fathers (those outside competitive environments) had the lowest testosterone levels compared to other males. [78]

Boldenone vs testosterone

boldenone vs testosterone

[ Editor's Note: Chryste Gaines, MBA, Olympic gold and bronze medal sprinter and former teammate of Marion Jones in the 2000 Sydney Olympic Games, stated the following in a Dec. 22, 2008 email to in response to the IOC ruling:

"We are being unfairly punished. If the drug testing agencies cannot determine if an athlete is taking performance enhancing drugs how are the teammates supposed to know?... It negates all the family functions, church functions, and social events we missed in the name of winning an Olympic medal." ]

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